CUED Publications database

Highly flexible, wearable, and disposable cardiac biosensors for remote and ambulatory monitoring.

Lee, SP and Ha, G and Wright, DE and Ma, Y and Sen-Gupta, E and Haubrich, NR and Branche, PC and Li, W and Huppert, GL and Johnson, M and Mutlu, HB and Li, K and Sheth, N and Wright, JA and Huang, Y and Mansour, M and Rogers, JA and Ghaffari, R (2017) Highly flexible, wearable, and disposable cardiac biosensors for remote and ambulatory monitoring. NPJ Digit Med, 1. 2-.

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Abstract

Contemporary cardiac and heart rate monitoring devices capture physiological signals using optical and electrode-based sensors. However, these devices generally lack the form factor and mechanical flexibility necessary for use in ambulatory and home environments. Here, we report an ultrathin (~1 mm average thickness) and highly flexible wearable cardiac sensor (WiSP) designed to be minimal in cost (disposable), light weight (1.2 g), water resistant, and capable of wireless energy harvesting. Theoretical analyses of system-level bending mechanics show the advantages of WiSP's flexible electronics, soft encapsulation layers and bioadhesives, enabling intimate skin coupling. A clinical feasibility study conducted in atrial fibrillation patients demonstrates that the WiSP device effectively measures cardiac signals matching the Holter monitor, and is more comfortable. WiSP's physical attributes and performance results demonstrate its utility for monitoring cardiac signals during daily activity, exertion and sleep, with implications for home-based care.

Item Type: Article
Uncontrolled Keywords: Electronic devices Translational research
Subjects: UNSPECIFIED
Divisions: Div C > Materials Engineering
Depositing User: Cron Job
Date Deposited: 13 May 2019 20:06
Last Modified: 24 Nov 2020 12:33
DOI: 10.1038/s41746-017-0009-x