CUED Publications database

From biophysical to integrate-and-fire modelling

Pottelbergh, TV and Drion, G and Sepulchre, R From biophysical to integrate-and-fire modelling. Neural Computation. ISSN 0899-7667 (Unpublished)

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This paper proposes a methodology to extract a low-dimensional integrate-and-fire model from an arbitrarily detailed single-compartment biophysical model. The method aims at relating the modulation of maximal conductance parameters in the biophysical model to the modulation of parameters in the proposed integrate-and-fire model. The approach is illustrated on two well-documented examples of cellular neuromodulation: the transition between Type I and Type II excitability and the transition between spiking and bursting.

Item Type: Article
Uncontrolled Keywords: q-bio.NC q-bio.NC
Divisions: Div F > Control
Depositing User: Cron Job
Date Deposited: 23 Jul 2020 03:05
Last Modified: 02 Sep 2021 05:31