CUED Publications database

Targeted regeneration of bone in the osteoporotic human femur

Poole, KES and Treece, GM and Ridgway, GR and Mayhew, PM and Borggrefe, J and Gee, AH (2011) Targeted regeneration of bone in the osteoporotic human femur. PLoS ONE, 6. ISSN 1932-6203

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Abstract

We have recently developed image processing techniques for measuring the cortical thicknesses of skeletal structures in vivo, with resolution surpassing that of the underlying computed tomography system. The resulting thickness maps can be analysed across cohorts by statistical parametric mapping. Applying these methods to the proximal femurs of osteoporotic women, we discover targeted and apparently synergistic effects of pharmaceutical osteoporosis therapy and habitual mechanical load in enhancing bone thickness. © 2011 Poole et al.

Item Type: Article
Subjects: UNSPECIFIED
Divisions: Div F > Machine Intelligence
Depositing User: Cron Job
Date Deposited: 07 Mar 2014 11:22
Last Modified: 13 Dec 2014 15:45
DOI: 10.1371/journal.pone.0016190