Lee, DS and Lee, JH and Luo, J and Fu, Y and Milne, WI and Maeng, S and Jung, MY and Park, SH and Yoon, HC (2009) A surface acoustic wave-based immunosensing device using a nanocrystalline ZnO film on Si. Journal of Nanoscience and Nanotechnology, 9. pp. 7181-7185. ISSN 1533-4880Full text not available from this repository.
The novelty of this study resides in the fabrication of a bio-sensing device, based on the surface acoustic wave (SAW) on a nanocrystalline ZnO film. The ZnO film was deposited using an rf magnetron sputtering at room temperature on silicon. The deposited films showed the c-axisoriented crystallite with grain size of ∼40 nm. The immunosensing device was fabricated using photolithographic protocols on the film. As a model biomolecular recognition and immunosensing, biospecific interaction between a 6-(2,4-dinitrophenyl) aminohexanoic acid (DNP) antigen and its antibody was employed, demonstrating the shifts of resonant frequencies on SAW immunosensing device. The device exhibited a linearity as a function of the antibody concentration in the range of 20∼20,000 ng/ml. © 2009 American Scientific Publishers. All rights reserved.
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