CUED Publications database

Electroosmotic flow analysis of a branched U-turn nanofluidic device.

Parikesit, GO and Markesteijn, AP and Kutchoukov, VG and Piciu, O and Bossche, A and Westerweel, J and Garini, Y and Young, IT (2005) Electroosmotic flow analysis of a branched U-turn nanofluidic device. Lab Chip, 5. pp. 1067-1074. ISSN 1473-0197

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Abstract

In this paper, we present the analysis of electroosmotic flow in a branched -turn nanofluidic device, which we developed for detection and sorting of single molecules. The device, where the channel depth is only 150 nm, is designed to optically detect fluorescence from a volume as small as 270 attolitres (al) with a common wide-field fluorescent setup. We use distilled water as the liquid, in which we dilute 110 nm fluorescent beads employed as tracer-particles. Quantitative imaging is used to characterize the pathlines and velocity distribution of the electroosmotic flow in the device. Due to the device's complex geometry, the electroosmotic flow cannot be solved analytically. Therefore we use numerical flow simulation to model our device. Our results show that the deviation between measured and simulated data can be explained by the measured Brownian motion of the tracer-particles, which was not incorporated in the simulation.

Item Type: Article
Uncontrolled Keywords: Computer Simulation Diffusion Electrochemistry Microfluidic Analytical Techniques Microfluidics Microscopy, Fluorescence Models, Statistical Models, Theoretical Nanotechnology Osmosis Poisson Distribution Static Electricity Surface Properties Time Factors
Subjects: UNSPECIFIED
Divisions: Div A > Turbomachinery
Depositing User: Cron Job
Date Deposited: 07 Mar 2014 11:27
Last Modified: 10 Mar 2014 17:24
DOI: 10.1039/b505493a