CUED Publications database

Size effects in indentation of hydrated biological tissues

Oyen, ML and Shean, TAV and Strange, DGT and Galli, M (2012) Size effects in indentation of hydrated biological tissues. Journal of Materials Research, 27. pp. 245-255. ISSN 0884-2914

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Abstract

Fluid flow in biological tissues is important in both mechanical and biological contexts. Given the hierarchical nature of tissues, there are varying length scales at which time-dependent mechanical behavior due to fluid flow may be exhibited. Here, spherical nanoindentation and microindentation testings are used for the characterization of length scale effects in the mechanical response of hydrated tissues. Although elastic properties were consistent across length scales, there was a substantial difference between the time-dependent mechanical responses for large and small contact radii in the same tissue specimens. This difference was far more obvious when poroelastic analysis was used instead of viscoelastic analysis. Overall, indentation testing is a fast and robust technique for characterizing the hierarchical structure of biological materials from nanometer to micrometer length scales and is capable of making quantitative material property measurements to do with fluid flow. © 2011 Materials Research Society.

Item Type: Article
Uncontrolled Keywords: Biological Nanoindentation Porosity
Subjects: UNSPECIFIED
Divisions: Div C > Biomechanics
Depositing User: Cron Job
Date Deposited: 07 Mar 2014 11:22
Last Modified: 08 Dec 2014 02:32
DOI: 10.1557/jmr.2011.322