CUED Publications database

Protein functionalized ZnO thin film bulk acoustic resonator as an odorant biosensor

Zhao, X and Ashley, GM and Garcia-Gancedo, L and Jin, H and Luo, J and Flewitt, AJ and Lu, JR (2012) Protein functionalized ZnO thin film bulk acoustic resonator as an odorant biosensor. Sensors and Actuators, B: Chemical, 163. pp. 242-246. ISSN 0925-4005

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ZnO thin film bulk acoustic resonators (FBARs) with resonant frequency of ∼1.5 GHz have been fabricated to function as an odorant biosensor. Physical adsorption of an odorant binding protein (AaegOBP22 from Aedes aegypti) resulted in frequency down shift. N,N-diethyl-meta-toluamide (DEET) has been selected as a ligand to the odorant binding protein (OBP). Alternate exposure of the bare FBARs to nitrogen flow with and without DEET vapor did not cause any noticeable frequency change. However, frequency drop was detected when exposing the OBP loaded FBAR sensors to the nitrogen flow containing DEET vapor against nitrogen flow alone (control) and the extent of frequency shift was proportional to the amount of the protein immobilized on the FBAR surface, indicating a linear response to DEET binding. These findings demonstrate the potential of binding protein functionalized FBARs as odorant biosensors. © 2012 Elsevier B.V. All rights reserved.

Item Type: Article
Divisions: Div B > Solid State Electronics and Nanoscale Science
Depositing User: Cron Job
Date Deposited: 17 Jul 2017 19:11
Last Modified: 26 Apr 2018 02:04