CUED Publications database

Spectroscopic characteristics and cellular compatibility of protein wrapped single wall carbon nanotubes

Bertulli, C and Beeson, HJ and Hasan, T and Ferrari, AC and Huang, YYS (2012) Spectroscopic characteristics and cellular compatibility of protein wrapped single wall carbon nanotubes. Proceedings of the IEEE Conference on Nanotechnology. ISSN 1944-9399

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Abstract

Non-covalent functionalization of CoMoCAT single-wall carbon nanotubes (SWNTs) by bovine serum albumin (BSA) was achieved. Photoluminescence spectra for the functionalized nanotubes showed good dispersion by BSA functionalization. Raman spectra were taken for the sonicated SWNT-BSA solution to establish the signal versus concentration correlation. Cellular uptake of functionalized carbon nanotubes by mouse macrophage (RAW264.7) was then investigated using Raman spectroscopy. For a seeding density of 50% confluence in a culture solution containing 10 μg/ml of BSA-SWNTs, uptake of 200 μg/ml by the macrophages was recorded after 23hr incubation, indicating an active uptake of SWNTs. © 2012 IEEE.

Item Type: Article
Subjects: UNSPECIFIED
Divisions: Div B > Solid State Electronics and Nanoscale Science
Div C > Biomechanics
Depositing User: Cron Job
Date Deposited: 07 Mar 2014 11:50
Last Modified: 08 Dec 2014 02:34
DOI: 10.1109/NANO.2012.6322192