CUED Publications database

Separating poroviscoelastic deformation mechanisms in hydrogels

Strange, DGT and Fletcher, TL and Tonsomboon, K and Brawn, H and Zhao, X and Oyen, ML (2013) Separating poroviscoelastic deformation mechanisms in hydrogels. Applied Physics Letters, 102. ISSN 0003-6951

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Abstract

Hydrogels have applications in drug delivery, mechanical actuation, and regenerative medicine. When hydrogels are deformed, load-relaxation arising from fluid flow - poroelasticity - and from rearrangement of the polymer network - viscoelasticity - is observed. The physical mechanisms are different in that poroelastic relaxation varies with experimental length-scale while viscoelastic does not. Here, we show that poroviscoelastic load-relaxation is the product of the two individual responses. The difference in length-scale dependence of the two mechanisms can be exploited to uniquely determine poroviscoelastic properties from simultaneous analysis of multi-scale indentation experiments, providing insight into hydrogel physical behavior. © 2013 American Institute of Physics.

Item Type: Article
Subjects: UNSPECIFIED
Divisions: Div C > Biomechanics
Depositing User: Cron Job
Date Deposited: 07 Mar 2014 11:22
Last Modified: 12 Dec 2014 19:04
DOI: 10.1063/1.4789368