CUED Publications database

Insula and striatum mediate the default bias.

Yu, R and Mobbs, D and Seymour, B and Calder, AJ (2010) Insula and striatum mediate the default bias. J Neurosci, 30. pp. 14702-14707.

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Abstract

Humans are creatures of routine and habit. When faced with situations in which a default option is available, people show a consistent tendency to stick with the default. Why this occurs is unclear. To elucidate its neural basis, we used a novel gambling task in conjunction with functional magnetic resonance imaging. Behavioral results revealed that participants were more likely to choose the default card and felt enhanced emotional responses to outcomes after making the decision to switch. We show that increased tendency to switch away from the default during the decision phase was associated with decreased activity in the anterior insula; activation in this same area in reaction to "switching away from the default and losing" was positively related with experienced frustration. In contrast, decisions to choose the default engaged the ventral striatum, the same reward area as seen in winning. Our findings highlight aversive processes in the insula as underlying the default bias and suggest that choosing the default may be rewarding in itself.

Item Type: Article
Uncontrolled Keywords: Adult Basal Ganglia Brain Mapping Cerebral Cortex Cognition Decision Making Female Humans Magnetic Resonance Imaging Male Motivation Neuropsychological Tests Observer Variation Psychomotor Performance Reward Task Performance and Analysis Young Adult
Subjects: UNSPECIFIED
Divisions: Div F > Computational and Biological Learning
Depositing User: Cron Job
Date Deposited: 07 Mar 2014 11:22
Last Modified: 22 Sep 2014 01:09
DOI: 10.1523/JNEUROSCI.3772-10.2010