CUED Publications database

Mechanics of biological networks: from the cell cytoskeleton to connective tissue.

Pritchard, RH and Huang, YYS and Terentjev, EM (2014) Mechanics of biological networks: from the cell cytoskeleton to connective tissue. Soft Matter, 10. pp. 1864-1884.

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Abstract

From the cell cytoskeleton to connective tissues, fibrous networks are ubiquitous in metazoan life as the key promoters of mechanical strength, support and integrity. In recent decades, the application of physics to biological systems has made substantial strides in elucidating the striking mechanical phenomena observed in such networks, explaining strain stiffening, power law rheology and cytoskeletal fluidisation - all key to the biological function of individual cells and tissues. In this review we focus on the current progress in the field, with a primer into the basic physics of individual filaments and the networks they form. This is followed by a discussion of biological networks in the context of a broad spread of recent in vitro and in vivo experiments.

Item Type: Article
Uncontrolled Keywords: Actins Biomechanical Phenomena Connective Tissue Cytoskeleton Elasticity Microtubules Rheology Stress, Mechanical
Subjects: UNSPECIFIED
Divisions: Div C > Biomechanics
Depositing User: Cron Job
Date Deposited: 17 Jul 2017 18:57
Last Modified: 19 Sep 2017 01:28
DOI: