CUED Publications database

Mechanical behaviour of electrospun fibre-reinforced hydrogels

Strange, DGT and Tonsomboon, K and Oyen, ML (2014) Mechanical behaviour of electrospun fibre-reinforced hydrogels. Journal of Materials Science: Materials in Medicine, 25. pp. 681-690. ISSN 0957-4530

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Mechanically robust and biomimicking scaffolds are needed for structural engineering of tissues such as the intervertebral disc, which are prone to failure and incapable of natural healing. Here, the formation of thick, randomly aligned polycaprolactone electrospun fibre structures infiltrated with alginate is reported. The composites are characterised using both indentation and tensile testing and demonstrate substantially different tensile and compressive moduli. The composites are mechanically robust and exhibit large strains-to-failure, exhibiting toughening mechanisms observed in other composite material systems. The method presented here provides a way to create large-scale biomimetic scaffolds that more closely mimic the composite structure of natural tissue, with tuneable tensile and compressive properties via the fibre and matrix phases, respectively. © 2014 Springer Science+Business Media New York.

Item Type: Article
Divisions: Div C > Biomechanics
Depositing User: Cron Job
Date Deposited: 17 Jul 2017 19:06
Last Modified: 22 May 2018 07:16