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Delayed-decision making in noisy bistable switches

Trotta, L and Bullinger, E and Sepulchre, R (2013) Delayed-decision making in noisy bistable switches. IFAC Proceedings Volumes (IFAC-PapersOnline), 12. pp. 84-88. ISSN 1474-6670

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Abstract

Bistable switches are frequently encountered in biological systems. Typically, a bistable switch models a binary decision where each decision corresponds to one of the two stable equilibria. Recently, we showed that the global decision-making process in bistable switches strongly depends on a particular equilibrium point of these systems, their saddle point. In particular, we showed that a saddle point with a time-scale separation between its attractive and repulsive directions can delay the decision-making process. In this paper, we study the effects of white Gaussian noise on this mechanism of delayed decision-making induced by the saddle point. Results show that the mean decision-time strongly depends on the balance between the initial distance to the separatrix and the noise strength. © IFAC.

Item Type: Article
Subjects: UNSPECIFIED
Divisions: Div F > Control
Depositing User: Unnamed user with email sms67@cam.ac.uk
Date Deposited: 18 May 2016 19:11
Last Modified: 28 Aug 2016 01:43
DOI: