CUED Publications database

Diagnostic Implementation of Fast and Selective Integrin-Mediated Adhesion of Cancer Cells on Functionalized Zeolite L Monolayers.

Greco, A and Maggini, L and De Cola, L and De Marco, R and Gentilucci, L (2015) Diagnostic Implementation of Fast and Selective Integrin-Mediated Adhesion of Cancer Cells on Functionalized Zeolite L Monolayers. Bioconjug Chem, 26. pp. 1873-1878.

Full text not available from this repository.

Abstract

The rapid and exact identification and quantification of specific biomarkers is a key technology for always achieving more efficient diagnostic methodologies. We present the first application of a nanostructured device constituted of patterned self-assembled monolayers of disk-shaped zeolite L coated with the cyclic integrin ligand c[RGDfK] via isocyanate linker, to the rapid detection of cancer cells. With its high specificity toward HeLa and Glioma cells and fast adhesion ability, this biocompatible monolayer is a promising platform for implementation in diagnostics and personalized therapy formulation devices.

Item Type: Article
Uncontrolled Keywords: Cell Adhesion Cell Separation HeLa Cells Humans Integrins Kinetics Ligands Nanotechnology Peptides, Cyclic Zeolites
Subjects: UNSPECIFIED
Divisions: Div E > Manufacturing Systems
Depositing User: Cron Job
Date Deposited: 17 Jul 2017 19:23
Last Modified: 17 Aug 2017 01:25
DOI: