CUED Publications database

A curcumin activated carboxymethyl cellulose-montmorillonite clay nanocomposite having enhanced curcumin release in aqueous media.

Madusanka, N and de Silva, KMN and Amaratunga, G (2015) A curcumin activated carboxymethyl cellulose-montmorillonite clay nanocomposite having enhanced curcumin release in aqueous media. Carbohydr Polym, 134. pp. 695-699.

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Abstract

A novel curcumin activated carboxymethylcellulose-montmorillonite nanocomposite is reported. A superabsorbent biopolymer; carboxymethyl cellulose (CMC) was used as an emulsifier for curcumin which is a turmeric derived water insoluble polyphenolic compound with antibacterial/anti-cancer properties. Montmorillonite (MMT) nanoclay was incorporated in the formulation as a matrix material which also plays a role in release kinetics. It was observed that water solubility of curcumin in the nanocomposite has significantly increased (60% release within 2h and 30 min in distilled water at pH 5.4) compared to pure curcumin. The prepared curcumin activated carboxymethylcellulose-montmorillonite nanocomposite is suitable as a curcumin carrier having enhanced release and structural properties.

Item Type: Article
Uncontrolled Keywords: Carboxymethylcellulose Clay Curcumin Nanocomposite Anti-Bacterial Agents Antineoplastic Agents Bentonite Carboxymethylcellulose Sodium Curcumin Drug Carriers Drug Liberation Kinetics Nanocomposites Solubility Water
Subjects: UNSPECIFIED
Divisions: Div B > Electronics, Power & Energy Conversion
Depositing User: Cron Job
Date Deposited: 17 Jul 2017 18:57
Last Modified: 23 Nov 2017 04:17
DOI: