CUED Publications database

Optimality of contraction-driven crawling

Recho, P and Joanny, JF and Truskinovsky, L (2014) Optimality of contraction-driven crawling. Physical Review Letters, 112. ISSN 0031-9007

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We study a particular mechanism of cell motility allowing a precise formulation of the condition of optimal trade-off between performance and metabolic cost. In the model, a steadily crawling fragment is represented by a layer of active gel placed on a frictional surface and driven by contraction only. We find analytically the distribution of contractile elements (pullers) ensuring that the efficiency of self-propulsion is maximal. We then show that natural assumptions about advection and diffusion of pullers produce a distribution that is remarkably close to the optimal one and is qualitatively similar to the one observed in experiments on fish keratocytes. © 2014 American Physical Society.

Item Type: Article
Divisions: Div C > Biomechanics
Depositing User: Cron Job
Date Deposited: 17 Jul 2017 19:35
Last Modified: 16 Jun 2018 20:16