CUED Publications database

Phosphopeptide Enrichment Using Various Magnetic Nanocomposites: An Overview.

Batalha, ÍL and Roque, ACA (2016) Phosphopeptide Enrichment Using Various Magnetic Nanocomposites: An Overview. In: UNSPECIFIED UNSPECIFIED, pp. 193-209.

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Abstract

Magnetic nanocomposites are hybrid structures consisting of an iron oxide (Fe3O4/γ-Fe2O3) superparamagnetic core and a coating shell which presents affinity for a specific target molecule. Within the scope of phosphopeptide enrichment, the magnetic core is usually first functionalized with an intermediate layer of silica or carbon to improve dispersibility and increase specific area, and then with an outer layer of a phosphate-affinity material. Fe3O4-coating materials include metal oxides, rare earth metal-based compounds, immobilized-metal ions, polymers, and many others. This chapter provides a generic overview of the different materials that can be found in literature and their advantages and drawbacks.

Item Type: Book Section
Uncontrolled Keywords: Affinity Hybrid material s Magnetic nanocomposite s Phosphopeptide enrich ment Aluminum Oxide Animals Ferrosoferric Oxide Humans Magnetite Nanoparticles Nanotechnology Peptide Mapping Phosphopeptides Phosphorylation Polymers Protein Processing, Post-Translational Proteomics Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Titanium Zirconium
Subjects: UNSPECIFIED
Divisions: Div B > Solid State Electronics and Nanoscale Science
Depositing User: Cron Job
Date Deposited: 17 Jul 2017 19:13
Last Modified: 16 Nov 2017 02:18
DOI: 10.1007/978-1-4939-3049-4_13