CUED Publications database

A microfluidic based differential plasmon resonance sensor

Okan, M and Balci, O and Kocabas, C (2011) A microfluidic based differential plasmon resonance sensor. Sensors and Actuators, B: Chemical, 160. pp. 670-676. ISSN 0925-4005

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A new type of differential surface plasmon (SPR) sensor integrated with a microfluidic system is presented. The working principle of the microfluidic device is based on hydrodynamic modulation of two laminar streams inside a microchannel to provide periodic changes of the environment on the SPR sensor. The modulated reflectance is then demodulated using a lock-in amplifier. The presented sensor provides sensitivities of index of refraction about 4 × 10-8 RIU together with a 4 orders of magnitude dynamic range. This method demonstrates a sensitive detection scheme which could be used for label-free detection. © 2011 Elsevier B.V. All rights reserved.

Item Type: Article
Divisions: Div B > Solid State Electronics and Nanoscale Science
Depositing User: Cron Job
Date Deposited: 22 Mar 2018 01:27
Last Modified: 24 Nov 2020 08:36
DOI: 10.1016/j.snb.2011.08.046